We DO NOT SELL to children or minors. Must be 21 or over to purchase.
Large handcarved natural tagua nut pipe with a nature-related design. Dimensions: approx. 7.5 in x 1.7 in x 2 in | 2-3 oz Clog free design with natural tagua nut bowl. Smoothed mouthpiece for style and comfort. Steel mesh screen filter provided. Tested for non-toxic materials. Handmade in Ecuador. Disclaimer: All tagua nut pipes will slightly vary in size and/or weight due to their authentic nature. We do not sell to minors or children, sales are for adults only. Must be 18 years (21 years in some states) or older to purchase. This product is intended for tobacco use only. It is your sole responsibility to know your state and local laws regarding the possession and use of tobacco pipes and accessories.
Large Tagua Nut Tobacco Smoking Pipe - Natural Carved Vegetable
Gut is a leading international journal in gastroenterology and hepatology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Gut delivers up-to-date, authoritative, clinically oriented coverage in all areas of gastroenterology and hepatology. Regular features include articles by leading authorities describing novel mechanisms of disease and new management strategies, both diagnostic and therapeutic, likely to impact on clinical practice within the foreseeable future.
Our new online collection highlights all research relating to the COVID-19 pandemic published by Gut, Frontline Gastroenterology and BMJ Open Gastroenterology. It is updated regularly as new articles are published.
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Iqgap3-Ras axis drives stem cell proliferation in the stomach
To cite: Sundar R, Liu DH, Hutchins GG, et al. Gut 2021;70:1833-1846.
Read the full article here: link
Objective: Tissue stem cells are central regulators of organ homoeostasis. We looked for a protein that is exclusively expressed and functionally involved in stem cell activity in rapidly proliferating isthmus stem cells in the stomach corpus.
Conclusions: IQGAP3 is a major regulator of stomach epithelial tissue homoeostasis and repair. The upregulation of IQGAP3 in gastric cancer suggests that IQGAP3 plays an important role in cancer cell proliferation.